Planning for translational research in genomics

Functional genomics in translational cancer research: focus on breast cancer.

Conventional molecular and genetic methods for studying cancer are limited to the analysis of one locus at a time. A cluster of genes that are regulated together can be identified by DNA microarray, and the functional relationships can uncover new aspects of cancer biology. Breast cancer can be used to provide a model to demonstrate the current approaches to the molecular analysis of cancer. Me...

Translational genomics

The term "Translational Genomics" reflects both title and mission of this new journal. "Translational" has traditionally been understood as "applied research" or "development", different from or even opposed to "basic research". Recent scientific and societal developments have triggered a re-assessment of the connotation that "translational" and "basic" are either/or activities: translational r...

Translational genomics of Vegetable Crops

Frontiers in Integrative Genomics and Translational Bioinformatics

1Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN 37203, USA 2Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN 37212, USA 3Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA 4Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, Sa...

What is translational genomics? An expanded research agenda for improving individual and population health

The mission of Applied and Translational Genomics is “to enhance the knowledge, clinical adoption and discussion of applied and translational genomics worldwide” [1]. But, it is still unclear what is meant by the term translational genomics. There are varying definitions of translational research [2] that have been applied to genomic medicine [3] and other areas (e.g., cancer survivorship resea...